Immunohistochemical markers used for diagnosis in pathological diseases

Immunohistochemical markers used for diagnosis in pathological diseases

Immunohistochemical markers used for diagnosis in pathological diseases:

1. Tumor of epithelial origin ( carcinomas) - cytokeratin.
2. Tumor of mesenchymal origin ( sarcoma) - vimentin
3. Tumor of smooth muscle origin ( leiomyoma) - smooth muscle actin, desmin
4. Tumor of skeletal muscle origin ( rhabdomyomas) - desmin, myogenin
5. Tumor of vascular origin ( angiosarcoma) - factor 8, von willebrand factor, cd 31
6. Tumor of glial origin ( gliomas) - glial fibrillary acidic proteinGFAP
7. Tumor o f hepatic origin ( HCC) - heppar1, alphafetoprotein